21C Museum Hotel Louisville

700 West Main Street, Louisville, United States of America - Show on map

The boutique-style 21C Museum Hotel Louisville includes 91 rooms and is 600 feet from Kentucky Science Center.

Location

Located 0.2 miles from Muhammad Ali Center Museum, this hotel is in close proximity to Louisville Slugger Museum & Bat Factory. Guests can quickly get to Belle of Louisville Riverboats Steamboat, which is about 10 minutes' walk away. The Louisville hotel is 1 mile from Waterfront Park. This accommodation is only steps away from Galt House bus station. 21C Museum Hotel Louisville is located 13 minutes' drive from Louisville airport.

Food & Drinks

The hotel is 7 minutes' stroll from Walker's Exchange and serves delectable meals.

Why choose 21C Museum Hotel Louisville

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Main amenities

  • Internet

  • 24-hour services

  • Wheelchair access

General
  • Internet
  • 24-hour services
  • Wheelchair access
1/3

Internet

  • Wi-Fi in public areas

Parking options

  • Parking

Property services

  • 24-hour reception
  • Dry cleaning

Recreation

  • Sauna

For disabled guests

  • Wheelchair access

Important information

Check-in:
from 16:00 until 23:59
Check-out:
until 11:00

Enter dates to see availability

From USD 0 per night
Check-in 1 Nov 2025
Check-out 2 Nov 2025
Guests 2 guests

Adults:

2

Children:

0
Special offers & deals Limited offer

Mobile-Only Deal

An exclusive discount – get up to 10% off when you book from your phone.

Members Only Rate

Up to 15% off
Join now to unlock up to 15% off on your dates – visible to members only.

Early Booking Discount

Up to 20% off
Save up to 20% when you book at least 30 days before your trip.

Family Package Deal

Up to 20% off
Save up to 20% with special family packages that include your stay, meals, and fun for the kids..

Summer Deal

Up to 15% off
Make the most of summer with up to 15% off and free breakfast – limited-time offer.

Rooms

Photos of 21C Museum Hotel Louisville

Location of 21C Museum Hotel Louisville

700 West Main Street, Louisville, United States of America

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    Enter dates to see availability
    From USD 0 per night
    Check-in 1 Nov 2025
    Check-out 2 Nov 2025
    Guests 2 guests

    Adults:

    2

    Children:

    0
    Check-in & out
    1 Nov 2025
    2 Nov 2025
    Guests
    2 guests
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    21C Museum Hotel Louisville
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    Details:

    700 West Main Street, Louisville, United States of America

    Important information
    21C Museum Hotel Louisville
    Check-in:
    from 16:00 until 23:59
    Check-out:
    until 11:00